Resistance to Oxidative Stress Is Associated with Metastasis in Mucocutaneous Leishmaniasis
نویسندگان
چکیده
منابع مشابه
Resistance to oxidative stress is associated with metastasis in mucocutaneous leishmaniasis.
Mucocutaneous leishmaniasis (MCL) in South and Central America is characterized by the dissemination (metastasis) of Leishmania Viannia subgenus parasites from a cutaneous lesion to nasopharyngeal tissues. Little is known about the pathogenesis of MCL, especially with regard to the virulence of the parasites and the process of metastatic dissemination. We previously examined the functional rela...
متن کاملPolymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis
Recent studies have shown that mucocutaneous leishmaniasis (MCL), a severe and debilitating form of American cutaneous leishmaniasis (ACL) caused by Leishmania braziliensis infection, is accompanied by high circulating levels of tumor necrosis factor (TNF)-alpha. Analysis of TNF polymorphisms in Venezuelan ACL patients and endemic unaffected controls demonstrates a high relative risk (RR) of 7....
متن کاملDiffuse mucocutaneous leishmaniasis.
Fig. 1 : Pappulonodular lesions over the face Fig. 2: Pappulonodular lesions over the tongue and soft palate Fig. 3: Smear biopsy of the skin lesion showing multiple amastigotes of Leishmania tropica intracellularly A 27 year old Hindu male, resident of district Barmer, Rajasthan , presented with multiple, diffuse, brownish, non umbilicated, papulonodular, non itchy, swellings of size 2 22 mm a...
متن کاملLoss of integration is associated with reduced resistance to oxidative stress.
One cellular mechanism thought to be particularly important as a constraint on lifespan and life-history strategies is oxidative stress. Susceptibility to oxidative stress is influenced by a number of antioxidant defences, whose effectiveness depends on the synergistic and competitive interactions among them (biochemical integration). It is generally assumed that exposure to oxidative stress is...
متن کاملThe Campylobacter jejuni Oxidative Stress Regulator RrpB Is Associated with a Genomic Hypervariable Region and Altered Oxidative Stress Resistance
Campylobacter jejuni is the leading cause of bacterial foodborne diarrhoeal disease worldwide. Despite the microaerophilic nature of the bacterium, C. jejuni can survive the atmospheric oxygen conditions in the environment. Bacteria that can survive either within a host or in the environment like C. jejuni require variable responses to survive the stresses associated with exposure to different ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2006
ISSN: 0022-1899,1537-6613
DOI: 10.1086/507646